Liverpool are currently 20 league games unbeaten, which is their joint-eighth longest ever run.
Palace signed 22-year-old centre-back Chris Richards from Bayern Munich during the summer and also added midfielder Cheick Doucoure for £22 million, two of five signings so far.
The Reds came from behind twice to rescue a 2-2 draw with Fulham on the opening weekend, while Patrick Vieira's side were no match for Arsenal in a 2-0 loss.
Recent history does not favour the visitors either, as Liverpool have won 10 Premier League games in a row against Crystal Palace since a 2-1 Anfield defeat in April 2017
Where can I watch?
It’s Monday night football and for those in the UK, that means the match is live on Sky Sports Main Event and Sky Sports Premier League, with coverage starting at 7pm (BST) ahead of the 8pm kick-off.